Chromogranin A

Included in meta analysis


Dittadi R, Meo S, Gion M, 2004, Clin Chem Lab Med, 42, 109-110 , Biological variation of plasma chromogranin A.


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,10,12,13

Item Details

Parameter Score
Matrix Serum
Measurand Chromogranin A
Unit ug / mL
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 22
Number of Subjects included in BV estimation 22
Ethinicity Caucasian
Age Mean / Median
Age Min 41.0
Age Max 60.0
Age SD
Number of Males 10
Number of Females 12
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 12.8
Calculated Confidence Intervals of CVi Lower: 11.12, Upper: 15.06
Estimates of CVg 26.3
Calculated Confidence Intervals of CVg Lower: 19.99, Upper: 37.67
Analytical CV 2.7
Calculated Confidence Intervals of Analytical CV Lower: 2.39, Upper: 3.11
Measurand Mean 83.0
Measurand Min 49.0
Measurand Max 122.0
Measurand SD