Creatine Kinase

Included in meta analysis


Wu AHB, Smith A and Wians F, 2009, Clin Chim Acta, 399, 109-11 , Interpretation of creatine kinase and aldolase for statin-induced myopathy: Reliance on serial testing based on biological variation


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand Creatine Kinase
Unit U / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 17
Number of Subjects included in BV estimation 17
Ethinicity Caucasian
Age Mean / Median
Age Min 19.0
Age Max 58.0
Age SD
Number of Males 9
Number of Females 8
State of Well Being
Healthy (excl pregnant)
Study Duration Length 49
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: unknown
End Time: unknown
Number of Samples 5
Average Number of Samples Used for BV Estimation 4.5
Average Number of Replicates 1.0
Estimates of CVi 29.5
Calculated Confidence Intervals of CVi Lower: 25.01, Upper: 35.99
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 1.1
Calculated Confidence Intervals of Analytical CV Lower: 0.71, Upper: 2.42
Measurand Mean
Measurand Min 65.0
Measurand Max 504.0
Measurand SD