Creatine Kinase

Included in meta analysis


Wu AHB, Smith A and Wians F, 2009, Clin Chim Acta, 399, 109-11 , Interpretation of creatine kinase and aldolase for statin-induced myopathy: Reliance on serial testing based on biological variation


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand Creatine Kinase
Unit U / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 17
Number of Subjects included in BV estimation 17
Ethinicity Caucasian
Age Mean / Median
Age Min 19.0
Age Max 58.0
Age SD
Number of Males 9
Number of Females 8
State of Well Being Healthy (excl pregnant)
Study Duration Length 49
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: unknown
End Time: unknown
Number of Samples 5
Average Number of Samples Used for BV Estimation 4.5
Average Number of Replicates 1.0
Estimates of CVi 29.5
Calculated Confidence Intervals of CVi Lower: 25.01, Upper: 35.99
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 1.1
Calculated Confidence Intervals of Analytical CV Lower: 0.71, Upper: 2.42
Measurand Mean
Measurand Min 65.0
Measurand Max 504.0
Measurand SD


© 2018 - 2019 This website and its content is copyright of EFLM. All rights reserved. Any redistribution or reproduction of part or all of the contents in any form is prohibited other than the following: you may print or download to a local hard disk extracts for your personal and non-commercial use only you may copy the content to individual third parties for their personal use, but only if you acknowledge the website as the source of the material You may not, except with our express written permission, distribute or commercially exploit the content. Nor may you transmit it or store it in any other website or other form of electronic retrieval system.
European Federation of Clinical Chemistry and Laboratory Medicine
Ms Silvia Cattaneo
Via Carlo Farini 81
20159 Milano - Italy