Reference
Carobene A, Roraas T, Solvik UO, Sylte MS, Sandberg S, Guerra E, Marino I, Jonker N, Barla G, Barlett WA, Fernández-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Coskun A, Serteser M, Unsal I and Ceriotti F, 2017, Clin Chem, 63, 1141-50 , Biological variation estimates obtained from 91 healthy study participants for 9 enzymes in serum
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Creatine Kinase |
| Unit | U / L |
| Overall Analytical Principle Method | Enzymatic analysis - Not specified |
| Number of Subjects | 35 |
| Number of Subjects included in BV estimation | 35 |
| Ethinicity | Caucasian |
| Age Mean / Median | 35.0 |
| Age Min | 22.0 |
| Age Max | 59.0 |
| Age SD | |
| Number of Males | 35 |
| Number of Females | |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 10 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
08:00
End Time: 10:00 |
| Number of Samples | 10 |
| Average Number of Samples Used for BV Estimation | 8.97 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 16.0 |
| Calculated Confidence Intervals of CVi | Lower: 14.77, Upper: 17.45 |
| Estimates of CVg | 31.5 |
| Calculated Confidence Intervals of CVg | Lower: 25.35, Upper: 41.33 |
| Analytical CV | 0.9 |
| Calculated Confidence Intervals of Analytical CV | Lower: 0.83, Upper: 0.98 |
| Measurand Mean | 134.5 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |