Haemoglobin A1c (NGSP)

Reference

Reference
Thyagarajan B, Howard AG, Durazo-Arvizu R, Eckfeldt JH, Gellman MD, Kim RS, Liu K, Mendez AJ, Penedo FJ, Talavera GA, Youngblood ME, Zhao L and Sotres-Alvarez D, 2016, Clin Chim Acta, 463, 129-137 , Analytical and biological variability in biomarker measurement in the Hispanic Community Health Study/Study of Latinos

Scoring

Total Score

C10

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
11. ANOVA A
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C10
Comment 1) Data may not be used for estimation of RCV (9B). 2) Data is not necessarily representative for the total population (10C).

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Haemoglobin A1c (NGSP)
Unit % / _
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 21
Number of Subjects included in BV estimation 21
Ethinicity Caucasian
Age Mean / Median 59.5
Age Min 45.0
Age Max 74.0
Age SD
Number of Males 21
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 36
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 5
Interval Units Year
Sampling Times Start Time:
End Time:
Number of Samples 18
Average Number of Samples Used for BV Estimation 18.0
Average Number of Replicates 2.0
Estimates of CVi 2.0
Calculated Confidence Intervals of CVi Lower: 1.84, Upper: 2.18
Estimates of CVg 20.62
Calculated Confidence Intervals of CVg Lower: 15.86, Upper: 29.47
Analytical CV 1.0
Calculated Confidence Intervals of Analytical CV Lower: 0.93, Upper: 1.08
Measurand Mean 5.8
Measurand Min
Measurand Max
Measurand SD

Coding