Haemoglobin A1c (NGSP)

Reference

Reference
Lenters-Westra E, Roraas T, Schidhelm RK, Sligerland RJ and Sandberg S , 2014, Clin Chem, 60, 1570-2 , Biological variation of hemoglobin A1c: consequences for diagnosing diabetes mellitus.

Scoring

Total Score

B2,3,5,7,8,9

Parameter Score
1. Scale A
2. Study Population B
3. Samples B
4. Measurand A
5. Pre-Analytical B
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score B2,3,5,7,8,9
Comment no age, no sampling time

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Haemoglobin A1c (NGSP)
Unit % / _
Overall Analytical Principle Method Chromatography; HPLC
Number of Subjects 21
Number of Subjects included in BV estimation 19
Ethinicity Unknown
Age Mean / Median
Age Min
Age Max
Age SD
Number of Males 11
Number of Females 10
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 2
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 1.0
Calculated Confidence Intervals of CVi Lower: 0.85, Upper: 1.20
Estimates of CVg 4.7
Calculated Confidence Intervals of CVg Lower: 3.56, Upper: 6.88
Analytical CV 0.4
Calculated Confidence Intervals of Analytical CV Lower: 0.35, Upper: 0.47
Measurand Mean 5.2
Measurand Min 5.17
Measurand Max 5.24
Measurand SD

Coding