Haemoglobin A1c (IFCC)

Included in meta analysis


Braga F, Dolci A, Montagnana M, Pagani F, Paleari R, Guidi GC, Mosca A and Panteghini M, 2011, Clin Chim Acta, 412, 1412-6 , Revaluation of biological variation of glycated hemoglobin (HbA1c) using an accurately designed protocol and an assay traceable to the IFCC reference system


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis A
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score B7,9

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Haemoglobin A1c (IFCC)
Unit mmol / mol
Overall Analytical Principle Method Immunoturbidimetry
Number of Subjects 18
Number of Subjects included in BV estimation 18
Ethinicity Caucasian
Age Mean / Median
Age Min 26.0
Age Max 52.0
Age SD
Number of Males 9
Number of Females 9
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 2.5
Calculated Confidence Intervals of CVi Lower: 1.91, Upper: 3.19
Estimates of CVg 7.1
Calculated Confidence Intervals of CVg Lower: 5.29, Upper: 10.60
Analytical CV 2.4
Calculated Confidence Intervals of Analytical CV Lower: 2.09, Upper: 2.81
Measurand Mean 36.3
Measurand Min
Measurand Max
Measurand SD